The NEXTFLEX?RiboNaut^™?rRNA depletion kit (human / mouse / rat) is a method which removes rRNA contamination while enabling labs to interrogate additional RNA species in a sample, not only limited to intact mRNAs. The kit utilizes biotinylated oligos complementary to rRNAs to pull them out of the sample using streptavidin-coated magnetic beads. The kit has been optimized for use with 5 ng – 1 µg of total RNA as starting material to deplete cytoplasmic and mitochondrial rRNAs. The kit has been tested to be compatible with human, mouse and rat, and it may be compatible with other mammalian species. Learn More.